Guadalupe ranked #1806 among U.S. baby names in 2024. Since 1880, 91,789 babies have been named Guadalupe, peaking in 1997 with 1,656 births. The 2000s were its biggest decade, with 14,566 births. Its use has been declining, down about 37% over the past five years. Guadalupe is given to both girls and boys.